A latent infection Essays

A latent infection Essays A latent infection Essay A latent infection Essay A latent infection refers to an infective agent, in this instance a virus, staying in an inactive or hibernating province [ I ] . This can happen in both DNA and RNA viruses, including Herpes Simplex virus and HIV. The virus life rhythm includes two parts, the lytic and lysogenic rhythm. Latent infections come under the lysogenic rhythm. This latent phase is utile in hedging an immune response so the virus lasts for a longer clip within the host cell. The lytic rhythm is the chief rhythm where reproduction occurs and is shown below in diagram 1. The first phase is attachment where the virus attaches to the host cell via a receptor. The viral nucleic acid is either injected into the cell through incursion or the whole virus atom is taken up by endocytosis. If the virus was taken up in this manner it now needs to be uncoated so the viral nucleic acid is exposed in the cytol of the host cell. The following phase is cistron look and the control of cistron look determines the overall class of a virus infection ( acute, chronic, relentless or latent ) ( Principles of Molecular Virology, 4th edition, Alan J. Cann, 2005 ) . Depending on the type of nucleic acid, DNA or RNA, look and reproduction of the cistron can take topographic point in the cytol or the karyon of the host cell. Assembly so takes topographic point to acquire all the constituents necessary to do a new virion together and they are packaged into membranes and envelopes. This is known as the ripening procedure and is the point when the virus becomes infective. Replication occurs rapidly and so many mature virions are made, that they are released from the host cell through lysis of the cell wall. The virions can now reiterate this procedure on another host cell to distribute the infection. Diagram 1 the lytic and lysogenic rhythms: Viral DNA/RNA is incorporated into the host genome in the lysogenic rhythm besides shown in diagram 1. The host genome is now termed a prophage and the viral nucleic acid replicates as a portion of the host cell and can be passed onto girl cells. No new virions are made in this rhythm and there are no symptoms from the infection. The viral nucleic acid can stay in the lysogenic rhythm for a long clip but if the prophage is triggered by emphasis or UV visible radiation, the rhythm can return back to the lytic rhythm where new viral offspring is formed. Viral latency is portion of the lysogenic component of the virus life rhythm. Gene look is down regulated so, in this latent province, the virus is non being replicated ( Janeway s Immunobiology, 7th edition, Murphy et Al, 2008 ) . The viral nucleic acid is integrated into the host genome and replicates with the host genome but no new viral proteins are being made. This happens at a point after the initial infection with the virus. There is no disease nowadays in this phase but the virus has non been eradicated. The virus can be reactivated from a latent province to a lytic province due to a figure of factors. These include emphasis, sunlight or hormonal alterations. A reversion to the lytic phase of the life rhythm consequences in viral proteins being made and the infection returning, but perchance in a different look compared to the initial infection. The latent province is maintained by the written text of certain cistrons, either maintaining the virus in the latent province or returning it back to the lytic. The forms of the latent phase can be studied utilizing bacteriophage lambda as it does non do disease. Diagram 2 below shows in graph signifier how the virus can travel in and out of a latent province over clip. Diagram 2 latency graph demoing viral burden vs. clip The virus in the latent phase does non bring forth any proteins, which makes it undetectable to the immune system as there are no sensing markers. The virus can besides conceal in cells that do non split, for illustration in some cells of the immune system. The virus does non acquire broken down or engulfed by macrophages as it has become portion of the host cell. The latent phase is a good manner of lasting in a host cell in order to reinfect the host subsequently on. It can so besides spread to other host cells, advancing drawn-out endurance and perennial infection. In a productive infection, the lytic rhythm is activated and viral proteins are made. This is different to the latent phase. The virus would merely last for a certain period of clip in a productive infection until it was eliminated from the host. Herpesviruses do latent infections in many different carnal species ( Introduction to Modern Virology, 6th edition, Dimmock et Al, 2007 ) . Herpesviruses can do different sorts of diseases, for illustration, poulet syphilis, the Herpes Simplex Virus and the Epstein-Barr virus. The Herpes Simplex Virus or HSV has many types, which include Type 1, associated with cold sores around the oral cavity and Type 2 with venereal herpes. Once infected with the HSV virus, it infects the mucose membranes around the oral cavity. The viral DNA of HSV1 so integrates into the host genome in nervus cells called nervous ganglion [ two ] . Viral look is restricted during the latent phase, so no viral offspring is formed. The virus can be in the latent phase and remain in the organic structure for the remainder of its life, perchance repeating at different phases. If the virus is reactivated from the latent phase, it goes into the lytic phase and replicates to organize new viral offspring, which reinfects the mucose membranes of the oral cavity. The new infection can besides look as a signifier of herpes zosters after reactivation. The latent phase of HSV1 has no effects on the host and no symptoms are produced from it unless reactivated into the lytic rhythm. Factors that affect the reactivation of HSV1 include other unwellnesss, for illustration a cold, sing nerve-racking state of affairss either emotionally or physically an d hurts. Within the nervous cells, in the latent phase, RNA sequences are expressed called Latency-associated Transcripts ( LATs ) . There are tonss of LATs and they modify procedures within the host cell so it is non removed by the immune system. This is the merely active portion of the virus during the latent phase and they help keep latency within the cell. LATs are besides required for reactivation. The Epstein-Barr virus or HHV-4 virus is besides portion of the herpes virus household. Peoples infected with the Epstein-Barr virus are frequently symptomless for most of their lives. If the infection arises in a kid, there is an acute infection. However, if the infection arises in an grownup, it can do glandular febrility. Symptoms include a sore pharynx, conceited secretory organs and a febrility [ three ] . The infection starts in the salivary secretory organ and can hence be dispersed direct contact with the septic spit, for illustration, through caressing. It lasts for around 2-3 hebdomads but after that clip, there are no longer symptoms and the virus remains latent in resting, memory B lymphocytes [ four ] . When the B cells are infected with EBV, they proliferate and T cells are recruited to acquire rid of septic B cells. Reactivation of the EBV virus frequently causes a subclinical infection but can besides do malignant neoplastic diseases, like Burkitt s lymphoma, largely found in Africa or B cell lymphoma. When the virus is in a latent province the cistrons are expressed in the round signifier of an episome, instead than a additive signifier in the lytic province. Upto nine viral proteins are expressed in the latent province which is a little sum compared to the viral proteins produced in the lytic province. These specific proteins help to keep the latent province. These include six Epstein-Barr atomic antigens ( EBNAs ) and three latent membrane proteins ( LMPs ) [ 5 ] . EBNA-1 is the lone one of these proteins which is necessary for DNA reproduction and the others are used in cell procedures like cell signalling. EBNA-1 is besides the lone antigen nowadays in Burkitt s lymphoma and T cells ca nt adhere with it, so ca nt acquire rid of the septic cell. Human Immunodeficiency virus ( HIV ) is a RNA retrovirus, which causes AIDS. AIDS is a status where the immune system has been degraded so much that it can no longer contend against infection. HIV contains 2 RNA strands and is covered by a protein coat. When HIV infects a cell, rearward RNA polymerase is used to change over its RNA into DNA so that reproduction can happen within the host. After infection, the virus either replicates quickly to infect other cells or goes into the latent province in CD4+ T lymphocytes. HIV is known as a slow virus which means it takes a long clip to bring forth symptoms, frequently taking to a late diagnosing of the disease. An infection with HIV causes flu like symptoms at first, before going symptomless and traveling into a clinically latent stage. In this stage there is still reproduction of the HIV virus in some cells but some of the virus has gone into a latent province, which means some of the virus is active and some is inactive. The clinical la tency phase varies in length from hebdomads to old ages and the virus can still be passed on to other people as the retroflexing virus is besides present. CD8 T cells are responsible for the diminution of the virus but they can non extinguish the virus. Peoples with the HIV virus carry the disease for the remainder of their lives. Anti-retroviral drugs and chemotherapy can non acquire rid of the virus from the latent phase, so even if the activated virus was eliminated, the virus can still re-emerge. The latent virus can be reactivated but the specific grounds for this happening are non known. Reactivation of the virus from the latent phase, consequences in more serious symptoms developing and leads to the oncoming of AIDS. To reason, latent infections are another manner that certain viruses can hedge the immune responses of the host. The virus can either conceal in cells in certain tissues like the Herpes Simplex Virus or conceal in B cells of the immune system like the Epstein-Barr virus. HIV is a RNA virus that prolongs the life of the virus by concealing in CD4+ cells. All these viruses can be reactivated to do a ulterior infection. Often the reverting infection is acute but sometimes more serious infections arise for illustration malignant neoplastic diseases like Burkitt s lymphoma upon reactivation of the EBV virus. The latency phase is a clever technique of the virus to remain in the host for a longer period of clip. hypertext transfer protocol: //dictionary.reference.com/browse/latent Latent Viruss and Diseases from World of Microbiology and Immunology. Â ©2005-2006 hypertext transfer protocol: //www.cdc.gov/ncidod/diseases/ebv.htm Introduction to Modern Virology, 6th edition, Dimmock et Al, 2007 hypertext transfer protocol: //www.science.org.au/nova/026/026key.htm

Navajo Adolescent Health Promotion Proposal Example

Navajo Adolescent Health Promotion Proposal Example Navajo Adolescent Health Promotion Proposal – Book Report/Review Example Navajo Adolescent Health Promotion Proposal Navajo Adolescent Health Promotion Proposal According to Collier, (2005),there is a significant relation between race and most health conditions. This implies that certain diseases affect particular races more than they do others. Age is another fundamental factor that seems to contribute to prevalence of certain diseases. The adolescents in Navajo are extremely vulnerable to obesity. There needs to be an intense promotional campaign on the health of Navajo adolescents. Experts who participate in such programs need to study the dietary intake of adolescents and their blood pressure. Proposals that intend to address the health of adolescents in this area should be supported. This is because such programs will help in eradication of such conditions as obesity (Griffiths & Weafer, 2004). A proposal that attempts to promote the health of adolescents in Navajo considers the causes of obesity. It also includes collaborations with significant heal th departments, for example, the Indian Health Service (IHS). This is because such departments offer significant amounts of funds that make such health proposals successful (Griffiths & Weafer, 2004). Navajo Indians will benefit when such proposals are successful because the health of adolescents will equally improve. There will also be prevention of further cases of obesity among the Navajo adolescents. Proposals that focus on fitness levels of the Navajo adolescents are significant in the entire promotion proposal phenomena (Weiner, 2013). Health promotion proposals in Navajo should focus on several interventions that include the same adolescents. The interventions should also educate them on the benefits of healthy feeding. Apart from this, the proposals need to consider inclusion of support groups to the obese adolescents.ReferencesGriffiths, C. T., & Weafer, L. F. (2004). Native North Americans: Crime, conflict, and criminal justice : a research bibliography. Vancouver, B.C.: C riminology Research Centre, Simon Fraser University.P.F. Collier, Inc. (2005). Health & Medical Year Book. New York: People Weekly Book.Weiner, I. B. (2013). Handbook of psychology: Volume 1. Hoboken, N.J: Wiley.

Invisible Man 3 Essay Example | Topics and Well Written Essays - 250 words

Invisible Man 3 - Essay Example Although it seems that in the modern society equality among races has been achieved, there remains to be a huge number of people who are represented by the main character in Invisible Man. Not only the African-American society struggles to find their own identity and value in a diverse community such as the United States, but also those from other continents of the world. Students as well as professionals from different ethnicities and culture do everything in order to make themselves fit in the American society. Social groups in different forms have started to exist in the society offering a sanctuary to those who feel neglected by other members of the community. Just like the main character in the novel, he found refuge in social groups such as the Brotherhood where he eventually though he has found his worth. However, as people become too attached to these groups, they eventually find out that this does not necessarily make them heard of their voices. In fact, the identity that they thought they had found in being a one among the members is not theirs but what the leaders of the group wanted them to be. In this reading, Ellison made it clear that embracing one’s individuality is the key to achieving peace to oneself. The desire of being accepted in the society is not achieved by seeking acceptance from other people and various social groups. The world itself is already filled with people who have prejudices among each other. Finding peace in oneself is the only key to being accepted in the society that is in itself already a

Thought questions 3 Coursework Example | Topics and Well Written Essays - 500 words

Thought questions 3 - Coursework Example The idea of portraying a witch as an old, poor and female was the idea of the Christians to portray the witches as a bad example. They even went to the extreme of portraying them as wrinkled, rugged, and bed-ridden individuals. The idea was to make people dislike the witches as they were portrayed as evil people. In actual sense, witches were of varying ages, and there were young witches who were not poor. Both males and females engaged witchcraft so the portrayal of witches as always being old, poor, and female was inaccurate. Massive outbreak in witch-hunt broke out during the 16th century. During this period, the Christians were undergoing a very important historic reformation known as the Protestant Reformation. Christians had previously hunted witches, but the Reformation seems to have contributed to the mind attribute that placed the devil in a manageable perspective. The reformation had somehow managed to create a link and a perception to relate witchcraft and the devil, which justified the execution of witches. Eighty percent of witch-hunt victims were women most of whom were single. They were also between ages 45 years and 65 years. Most of them were at the bottom in the social status, nearly 80 percent. Most of them were disliked, quarrelsome and poor. Initially, witches were tried using the accusatory justice where they were presumed guilty until proved otherwise. The Christians latter popularized another system, inquisitorial type of justice where the defendant was innocent until proved otherwise. This method required that the one convicted of witchcraft give a confession. This was latter altered, and torture was included to obtain a confession from the accused witches. Free and voluntary confession by the suspected person of the crime made, examination and subsequent accusations were a ground of conviction. Another criterion was the affirmation of two credible persons under oath that they had witnessed the accused doing

Human and Plant Physiology Coursework Example | Topics and Well Written Essays - 1000 words

Human and Plant Physiology - Coursework Example The mesophyll tissue, which is made up of spongy cells, and palisade cells contain a huge number of chloroplasts. Chloroplasts contain chlorophyll (a green pigment) which absorbs light energy during photosynthesis. The leaf’s palisade tissue contains the greatest concentration of chloroplasts and it is in this tissue where most photosynthesis takes place (Adds, Larkcom, and Miller 2004, p3). Explain the Exchange of Oxygen and Carbon Dioxide between the Plant and Its Environment Gaseous exchange indicates the exchange of oxygen and carbon dioxide between the plant and its environment or surrounding. There are two processes of gaseous exchange, photosynthetic gas exchange and respiratory gas exchange. In photosynthetic gas exchange, carbon dioxide is taken up and oxygen given off by the plant. On the other hand, in respiratory gas exchange, the plant takes up oxygen and gives off carbon dioxide. The process that predominates at a certain time can be determined at the leaf surfac e of the assimilating plant. Respiratory carbon dioxide escapes when it is dark. Under optimal conditions for assimilation, photosynthesis is maintained by the utilization of carbon dioxide set free through respiration. This state of compensation is only evident when the process of gas exchange is shut off. It is important to note that gas exchange between the plant cells and its surroundings or the environment takes place by mass flow and diffusion (Larcher 2003, p91). Explain the Uptake of Water and Minerals by the Plant After the diffusion of mineral-rich soil water into the roots, the water reaches the vascular cylinder of the root through two ways, (a) by diffusing through the cell wall, and (b) by moving through the cytoplasm. Water enters the cytoplasm through the diffusion across the plasma membrane of the cell in the root’s cortex or epidermis. Dissolved mineral cannot diffuse because the membranes are impermeable to ions (Evers, Starr, and Starr 2010, p418). Mineral ions enter the cytoplasm through the active transport process in the plasma membranes. In the cytoplasm, ions and water diffuse from one cell to the cell through plasmodesmata until they enter the vascular cylinder. After water and ions enter the vascular cylinder, they are distributed to the other parts of the plant by the xylem. The plant’s cell wall is rigid but permeable to ions and water. Soil water can enter vascular cylinder by direct diffusion through the cell walls. The parenchyma cells in the root cortex are tightly packed, and they create a continuous pathway that permits the diffusion of mineral ions and water into the vascular cylinder from the epidermis. It is important to note that soil water diffusing into through the cell wall enters the vascular cylinder through the endodermal cell cytoplasm (Evers, Starr, and Starr 2010, p419). Analyse the Benefits of Exercise and the Problems Associated With Obesity There are numerous health benefits of exercise. Exercise can minimize major illnesses such as stroke, diabetes, cancer, and heart disease by up to 50 percent. Exercise can lower up to 30 percent the risk of early death in an individual. Research indicates that physical activity or exercise can boost mood, energy, sleep quality, and self-esteem. Physical activity has been shown to reduce the risk of depression, Alzheimer’s disease, dementia, and stress. People who do exercise regularly

Fiduciary Duties

Fiduciary Duties 1.0 Introduction Fiduciary duty refers to a legal duty for an individual to act on behalf of another particular in order to make a relationship of confidence and trust (Davies, 2007). It consists of the set of moral value such as trust, honesty and confidence; fiduciary duty can be obviously seen in the relationship between the shareholders and the board of directors as the BOD are managing the company’s affairs on behalf of the shareholders. However, there is no legal duty between the relationship of individual shareholders and board of directors. Individual shareholders are unable to against the board of directors if the BOD causes any damage unless the company give permission to sue them on behalf of shareholders as BOD and shareholders are separate legal entity. Fiduciary duty is a common law however due to some unethically act of directors, government codified the directors’ duties under section 171 to 177 of Companies Act 2006 so that directors will act in good faith and best inte rest of the company. As these duties had been legalized under Companies Act 2006, the board of directors of every company are binding to these duties as the role of directors. Example of the role of directors are acting within the powers, promoting the success of the company, exercising independent judgement, exercising reasonable care, skill and diligence, avoiding conflict and declaring interest in proposed transactions or arrangement (Davies, 2007). It is very crucial for the BOD to abide the duties as they are managing the company’s affairs. 2.0 Duty to act within powers (Section 171 of Companies Act 2006) In this section directors are required to exercise their power in the company’s constitution. Besides, they are not allows to use their power for any improper purposes such as issue shares for purpose of creating new majority within the company to gain control even though directors honestly believe their act is in the best interest of company; directors can only use their power for purposes which they were conferred or given. It is stated clearly in Section 171 of Companies Act 2006: â€Å"(a) directors are required to act in accordance with the company’s constitution (b) exercise power for purposes for which they are conferred†. This principle implemented in Hogg v Cramphorn in UK. In this case, Colonel Cramphorn has abused his powers by issuing shares to stop Baxter from taking over the company. He also convinced other directors to vote against the takeover by issuing share capital. Although he believes that this action was the bona fide for the company’s interest, this case was held as breach of directors’ duties due to exercise power for an improper motive and it is considered as ultra vires (Mantysaari, 2005). However, this principle does not consider as a breach of duty in Teck Corporation Ltd v Millar in Canada. This is because directors have to consider the reputation, experience and policies of people who are willing to take over the company before the new shares issued. Besides, they are also allowed to use their powers to protect the company if the takeover may cause significant damage to the interest of company (Kershaw, 2012). 2.1Duty to Promote the Success of the Company (Section 172 of Companies Act 2006) Under this statutory, directors are obligated to this duty to act in good faith and act in the way that they consider to enhance the development of the company and get benefits for all members in the company. Moreover, in this section government also requires directors to take account of six factors in the decision making process. Consequently, Section 172 of CA 2006 provides that: â€Å"(1)A director of a company must act in the way he considers, in good faith, would be most likely to promote the success of the company for the benefit of its members as a whole, and in doing so have regard (amongst other matters) to— (a)the likely consequences of any decision in the long term, (b)the interests of the companys employees, (c)the need to foster the companys business relationships with suppliers, customers and others, (d)the impact of the companys operations on the community and the environment, (e)the desirability of the company maintaining a reputation for high standards of business conduct, and (f)the need to act fairly as between members of the company.† The term â€Å"have regard† in section 172(1) indicates that government leave the decisions of how they implement the individual factors to directors. Furthermore, it is also no requirement for directors to give precedence of any factors; as directors take account of any listed factors or any relevant factors in the decision making process they are considered already fulfilled their duties in this section. The case law in this statutory concerned about the directors should exercise in best interest of the company rather than the principle of promoting the success of the company directly. For example the case of Hogg v Cramphorn, in order to take over the company, directors abused their power by issuing shares to create new majority within the company (Mantysaari, 2005). Under this section, directors must use their powers for intended purposes not collateral purposes and always act in the best interest of company. 2.2 Duty Not to Accept Benefits from Third Parties (Section 176 of Companies Act 2006) The principle of this duty is stated clearly in the statutory. The benefits that accepted from third parties[1] by the directors are considered as breach of directors reason being provided in s.176(1) is because of theirs’ position or directors may do or not do as a director. This statutory also states that directors can only accept the benefits that paid by someone’s services as a director or otherwise to the company and benefits that will not affect the conflict of interest. Section 176 of the Companies Act 2006 provides that: â€Å"(1)A director of a company must not accept a benefit from a third party conferred by reason of— (a)his being a director, or (b)his doing (or not doing) anything as director. (2)A â€Å"third party† means a person other than the company, an associated body corporate or a person acting on behalf of the company or an associated body corporate. (3)Benefits received by a director from a person by whom his services (as a director or otherwise) are provided to the company are not regarded as conferred by a third party. (4)This duty is not infringed if the acceptance of the benefit cannot reasonably be regarded as likely to give rise to a conflict of interest. (5)Any reference in this section to a conflict of interest includes a conflict of interest and duty and a conflict of duties.† One of the examples that breach the duty not to accept benefits from third parties is Tesco Stores v Pook. In this case, Mr Pook, the senior employee, fabricated false invoices about  £500,000 and accepted a bribe of total  £323,749 from third parties. He also denied that the payment is not a bribe but it is a start up loan for his business. However, Judge Peter Smith held that the money is a bribe as the means of false invoices and fraudulent value added tax had documented by the payers. Judge Peter Smith held that the bribe will be accounted on constructive trust based on the case of Attorney-General for Hong Kong v Reid[2] (Fisher, 2003). 2.3 Duty to Exercise Reasonable Care, Skill and Diligence (Section 174 of Companies Act 2006) Generally, this duty was a common law duty which required directors to act with reasonable care, and skill; yet, government codified it under section 174 of Companies Act 2006 by imposing the objective and subjective of standards of care to directors. Directors are obligated to act reasonable care, skill and diligence which indicated by the term of â€Å"must† under s.174(1). â€Å"(1)A director of a company must exercise reasonable care, skill and diligence.† Also, directors are required to follow the subjective and objective standards of care that states in section 174(2) in order to fulfil the standard of competence given. Section 174(2) of Companies Act 2006 provides that: (2)This means the care, skill and diligence that would be exercised by a reasonably diligent person with— (a)the general knowledge, skill and experience that may reasonably be expected of a person carrying out the functions carried out by the director in relation to the company, and (b)the general knowledge, skill and experience that the director has. Under this section, directors are not liable if the negligence found to be honest ought to be excused. It can be seen in the case of Re City Equitable Insurance Co Ltd that held by Romer J where the chairman of the company, Mr Bevan had committed fraud which caused the company loss of  £1,200,000 in the investments. Romer J held that even other directors and auditors involved in this case due to negligence as overlooked the fraud and signed a blank cheque for Bevan, they were honest and still acting in the degree of both still and diligence. Therefore, they’re not suspicious and not liable (Chan, 2009). 3.0 Conclusion In conclusion, there is no effective control on the board of directors even there is statutes as the relationship between board of directors and shareholders are based on fiduciary duty (trust) not legal duty. Therefore, there is no direct remedy for shareholders to against the board of directors as the board of directors only represented shareholders fiduciary. If board of directors had breached their duties, individual shareholders are not allowed to sue the board of directors because shareholders and the board of directors are two separate entities. Besides, when the board of directors breach their duties, the â€Å"victim† is the company not the shareholders. Hence, only the company can sue the board of directors only if the board of directors agrees to sue. Individual shareholders can only against the board of directors if the company accept or individual shareholders are able to raise the issue of minority protection. However, there are remedies to against the board of d irectors due to breach of director duties. The company allows to against the directors who make a mistake at their duties that causes loss in the company. Additionally, directors who make a mistake at their duties can be asked for compensation by the company due to their negligence. Moreover, company can also void the contract that director has an undisclosed interest (Davies, 2007). Parmalat Scandal (2003) Parmalat is an international corporate that produces dairy products which based in Italy. As this company is owned by family members, it causes the lack of transparency of the company which may not only harm the company but also the shareholders. This had led to the scandal of breach of director duties on financial fraud and money laundering in year 2003 by the senior executives of the company and causes 15,000 employees loss their jobs. In December 2003, Parmalat declared bankrupt as the company has a huge debt about â‚ ¬14 billion excluding the â‚ ¬4 billion hole in the company’s accounts due to financial fraud and money laundering (Chalkidou, 2011). This scandal also known as â€Å"brazen fraud†; it was started in mid-November where auditors and banks look into Parmalat’s accounts when the company defaulted on a bond payment which cost â‚ ¬185 million. They realized that one of bank accounts in Cayman Island which holding â‚ ¬4 billion did not exis t (Chalkidou, 2011). The company also fake the statement of financial position by overstated the assets in order to hide the liabilities of â‚ ¬16.2 billion over a fifteen-year period. Moreover, Parmalats CEO also embezzled about â‚ ¬620 million to cover losses of other family-owned corporate (Chalkidou, 2011). There are about 20 individuals that involved in this scandal were sentence in jail included Calisto Tanzi, the founder and Chief Executive Officer of Parmalat and Fausto Tonna, the Chief Financial Officer of company (Tanner, 2010). Both of them where sentence in jail for 18 years and 14 years respectively; whereas, Giovanni Tanzi, Calisto’s brother where sentence 10 years in jail. Other former directors were also sentence in jail for less than 10 years. [1] Third parties refer to company or individual who acting on behalf of an associated body corporation. [2] In the case of Attorney-General for Hong Kong v Reid, it is held that the bribes should consider as constructive trust so that fiduciaries will not have gain any benefits from their illegal behaviour.

Greek Myth Book Report: Prometheus Steals Fire From Heaven :: essays research papers

Greek Myth Book Report: Prometheus Steals Fire From Heaven Title - Prometheus Steals Fire From Heaven Author - Shortened, Simplified version of real story. Author Unknown I. Setting:   Ã‚  Ã‚  Ã‚  Ã‚  The setting for the story Prometheus Steals Fire From Heaven is In heaven, Earth, Olympus, and Mt. Caucasus. The time period is that of when there were only the (Greek) gods, and no men on earth, and none of the animals seemed worthy to rule the rest. II. Point of View: Omniscient point of view III. Characters: Zeus - Zeus is the ruler of the universe. At one point in the story Zeus was Jealous of others' powers. Zeus also had a bad temper and was mad at Prometheus for stealing heavens fire and chained Prometheus high on Mt. Caucasus, forever. He is one of 2 antagonists in the story. Hera - Queen of heaven, no significant part in story. Prometheus - The major protagonist in the story. Prometheus was one of the Titans (parents of the gods). He always thought of the positive side of things, and never let anyone or thing phase him. He proudly endured pain and showed his agony to none, all for inferior humans. Epimetheus - A minor part in the story. Epimetheus was the brother of Prometheus. Hephaestus - This minor character is heaven's lame smith. His part is somewhat significant later in the story, but he has no say in what he does, even if it is wrong. Pandora - Pandora was made by Zeus. She was made to curb man's power. As beautiful as a goddess, the immortals bestowed gifts on her to make her more captivating. Pandora is the 2nd antagonist in the story. IV. Theme   Ã‚  Ã‚  Ã‚  Ã‚  The hero's mission is to create a man like figure on the Earth, with the power of fire. Pandora accidentally opened a jar full of disease, envy, revenge, spite, and other evils which went on man, down on the earth, but she closed it. The only thing left in it was hope. That is all man had now - hope. Prometheus completed his mission, even though he was chained up on the side of the mountain and tormented the rest of his life. V. Plot   Ã‚  Ã‚  Ã‚  Ã‚  There was a time when there was no gods, and Heaven and Earth alone existed. From their union sprung the Titans, and the children of the Titans, the gods rebelled and overthrew them. Now there was no men on Earth so Prometheus had a task of making one. He mixed clay with water, kneaded it, shaped it, and made it look rather god like in shape. He made it stand upright Greek Myth Book Report: Prometheus Steals Fire From Heaven :: essays research papers Greek Myth Book Report: Prometheus Steals Fire From Heaven Title - Prometheus Steals Fire From Heaven Author - Shortened, Simplified version of real story. Author Unknown I. Setting:   Ã‚  Ã‚  Ã‚  Ã‚  The setting for the story Prometheus Steals Fire From Heaven is In heaven, Earth, Olympus, and Mt. Caucasus. The time period is that of when there were only the (Greek) gods, and no men on earth, and none of the animals seemed worthy to rule the rest. II. Point of View: Omniscient point of view III. Characters: Zeus - Zeus is the ruler of the universe. At one point in the story Zeus was Jealous of others' powers. Zeus also had a bad temper and was mad at Prometheus for stealing heavens fire and chained Prometheus high on Mt. Caucasus, forever. He is one of 2 antagonists in the story. Hera - Queen of heaven, no significant part in story. Prometheus - The major protagonist in the story. Prometheus was one of the Titans (parents of the gods). He always thought of the positive side of things, and never let anyone or thing phase him. He proudly endured pain and showed his agony to none, all for inferior humans. Epimetheus - A minor part in the story. Epimetheus was the brother of Prometheus. Hephaestus - This minor character is heaven's lame smith. His part is somewhat significant later in the story, but he has no say in what he does, even if it is wrong. Pandora - Pandora was made by Zeus. She was made to curb man's power. As beautiful as a goddess, the immortals bestowed gifts on her to make her more captivating. Pandora is the 2nd antagonist in the story. IV. Theme   Ã‚  Ã‚  Ã‚  Ã‚  The hero's mission is to create a man like figure on the Earth, with the power of fire. Pandora accidentally opened a jar full of disease, envy, revenge, spite, and other evils which went on man, down on the earth, but she closed it. The only thing left in it was hope. That is all man had now - hope. Prometheus completed his mission, even though he was chained up on the side of the mountain and tormented the rest of his life. V. Plot   Ã‚  Ã‚  Ã‚  Ã‚  There was a time when there was no gods, and Heaven and Earth alone existed. From their union sprung the Titans, and the children of the Titans, the gods rebelled and overthrew them. Now there was no men on Earth so Prometheus had a task of making one. He mixed clay with water, kneaded it, shaped it, and made it look rather god like in shape. He made it stand upright

Homosexuality vs Society

Homosexuality in today’s society In today's society, there exists a mixture of issues which tend to raise arguments with people all over. There are a handful of topics that always seem to escalate these differences between people to the point where one who participates in debate and argument can direct their anger towards their feelings on the person themselves. An issue that has in recent years, begun to increase arguments, is the acceptability of homosexuality in society. Until recently, homosexuality was considered strictly taboo.If an individual was homosexual, it was considered a secret to be kept from all family, friends, and society. However, it seem that society has begun to accept this lifestyle by allowing same sex couples. The idea of coming out of the ‘closet' has moved to the head of homosexual individuals when it used to be the exception. Homosexuality is nothing to be ashamed of and we should all come to realize this. The United States is denying good peop le a better life based on sexual orientation. Acceptance of homosexual marriage is a major issue in today’s society.This is a civil. issue, and the United States needs to start realizing that they are denying marriage rights to homosexuals because of moral reasons. What ever happened to separation of church and state? Opponents of homosexual marriage feel that by allowing gay and lesbians the right to marriage undermines the traditional definition of marriage. However, as society changes and the demands of the American citizens change, there needs to be changes that comply with not only the traditional society but also with modern needs of the United States people.Not only are homosexual couples being denied marriage rights but also adoption rights in several states. There would be no harm to society by allowing homosexuals the right to marriage or to legally adopt; the positive impacts it would have on society are far greater then the negative effects. Homosexuals should get the same rights as any other United States citizen. For the United States to have a functional society, allowing all citizens, regardless of sexual preference, would be in everyone’s best interest to allow homosexuals the right to arry. Looking back at history, it was not that long ago that black and white marriages were not accepted in society. Accepting black and white marriages has made the United States a stronger society. Gay and lesbian marriages would not harm anyone; however, it would improve and enhance the lives of those couples involved. Allowing gay marriage would have positive effects on children to gay couples; in addition, allowing homosexuals to marry and adopt would help place some children, who may never be placed into a family, find families through adoption.Homosexuals can be found in every race, religion, age group, country, state, and social group. Discrimination toward homosexuals persecute their choice of lifestyle. The issues of military employment, legal rights for couples, and acceptance within society need to resolved. Some ways to help put an end to this discrimination is to put the military services on a legislative plan prohibiting discrimination against homosexuals, allow for couples to be legally married. People need to realize that homosexuals are just like them.Homosexuals are found everywhere and are good people and need to be recognized not for their sexuality, but for who they are. The problem lies with the heterosexuals, those who establish firm opinions against gays, based solely off of stereotypical thinking, or their own feelings, rather than rational or factual information. One of these stereotypes tends to be that lesbians want to act and look like men, and vice versa. Although this may be the case in some homosexuals, it is not true for every single individual, thus a biased stereotype is formed.A stereotype such as this may cause an extreme hostile attitude, as well as discrimination, against a homosexual i ndividual. Also, homosexual jokes are constantly made every day. As funny as this may be to a heterosexual, imagine how this single joke could damage a gay man's self-esteem or even his social acceptance. A straight male or female could easily laugh at this joke, as many have, while a gay man hears this joke and takes it to heart. He could easily feel inferior to a straight male, or just as easily be offended by the use of the word fag.Society doesn't realize when certain words are used, they can offend a variety of people. Not to mention, the words gay, fag and queer have found their way into our everyday vocabulary, all of which can cause different emotions to different people. For instance, when someone says â€Å"That's so gay† a heterosexual would view the word gay as meaning strange or different, which completely changes the meaning of the word and associates homosexuals with being weird. ?Many Heterosexuals believe we must not pass any laws regarding discrimination of homosexuals.If we didnt pass the law about discrimination, the homosexual man and his lover would have to continue searching because they were denied equal treatment as a straight man. This unequal treatment is the reason homosexuals are trying so hard to gain a law against discrimination. There is also no justification to deny a specific occupation to a homosexual, because of their sexual orientation, unless there is a threat to an individual. For instance a homosexual man wants to become an accountant. What is keeping him from accomplishing this goal?A major hindrance-a state licensing law. The same goes if another homosexual would like to become a hairdresser, or perhaps even a used-car dealer. This same Law prevents people with certain sexual orientations from achieving their goals in life. This is not the American dream so many have heard about. America is supposedly the land of the free, a land of equal opportunity. There isn't any equality found between a straight man and a g ay man. ? â€Å"Queerbashing† is one of the most extreme forms of discrimination to homosexuals, and seems to be taken very lightly in court.A district of Columbia judge had listened to the story of a young homosexual male who had been stalked, beaten, stripped at knifepoint, slashed, kicked and urinated on by a couple of young queerbashers. The judge believed these queerbashers were â€Å"good boys† at heart because they attended a religious prep school, and suspended their sentences. These young men were obviously guilty for beating up another person and various other reasons, but were set free with virtually no penalty because they went to a certain ‘good' school.This is completely unjust in the fact these boys got off the hook without paying a penalty for the physical, emotional and mental abuse they put this homosexual boy through. â€Å"Police and juries often will simply discount testimony from gays; they frequently construe assaults on and murders of gay s as â€Å"justified† self-defense. ?Discrimination against homosexuals has been in existence since before our time and can be found all over our planet, yet it has only just recently become an active fight, between heterosexuals and homosexuals, over the fact that it shouldn't even exist in the first place.Alliances between gay and straight men and women have been formed over the years and continue to grow in population. These men and women, of any sexual-orientation, joined these groups for support and help to aid in the process of becoming equal united states citizens. Together they can recruit new members and maybe one day even get rid of discrimination completely. In order to achieve equality in our nation, we must keep our mind open to new ideas and events and give homosexuals a chance to become human beings.

Free Essays on Women On Welfare

The percentage of women on welfare is staggering, whereas there are far fewer men relying on the system. Although the level of discrimination against women on welfare has decreased somewhat, it is still a major concern in comparison to men. For many centuries women have had to rely on men for survival. In the early 1900’s,for example, women were married at a young age and were taught only how to clean house and take care of their husbands. Education was not part of a woman’s lifestyle. Today, however, little girls are now being taught to be independent educated women. This means that, we, as women do not have to rely on men to survive- or so that is what I believed until I found myself separated from my first husband. I was living a comfortable lifestyle with three children. It was not until I saw my ex-husband’s money go out the door with him that I realized how dependant on him I was. With no education (I dropped out at 15) and no job, I found myself relying on social assistance and then onto mother’s allowance. My ex-husband did not pay his child support and even if he had of paid it; welfare would take it away from me because it is considered extra income. Once comfortable and living easy without having to worry about where my next meal was coming from, I was now living in poverty. I will discuss this more in detail later. The differences between women and men on welfare are quite significant. My findings are alarming because of all the data that I have found shows that although women are more likely to be the single parent, they are more apt to rely on social assistance than the male single parent. As well, women, with or without children, are living in poverty far more often than males are. The poverty rate among women who are receiving social assistance is high at 55 percent, whereas women who are not receiving social assistance, the poverty rate for non-elderly women are 17 percent. For unattached wo... Free Essays on Women On Welfare Free Essays on Women On Welfare The percentage of women on welfare is staggering, whereas there are far fewer men relying on the system. Although the level of discrimination against women on welfare has decreased somewhat, it is still a major concern in comparison to men. For many centuries women have had to rely on men for survival. In the early 1900’s,for example, women were married at a young age and were taught only how to clean house and take care of their husbands. Education was not part of a woman’s lifestyle. Today, however, little girls are now being taught to be independent educated women. This means that, we, as women do not have to rely on men to survive- or so that is what I believed until I found myself separated from my first husband. I was living a comfortable lifestyle with three children. It was not until I saw my ex-husband’s money go out the door with him that I realized how dependant on him I was. With no education (I dropped out at 15) and no job, I found myself relying on social assistance and then onto mother’s allowance. My ex-husband did not pay his child support and even if he had of paid it; welfare would take it away from me because it is considered extra income. Once comfortable and living easy without having to worry about where my next meal was coming from, I was now living in poverty. I will discuss this more in detail later. The differences between women and men on welfare are quite significant. My findings are alarming because of all the data that I have found shows that although women are more likely to be the single parent, they are more apt to rely on social assistance than the male single parent. As well, women, with or without children, are living in poverty far more often than males are. The poverty rate among women who are receiving social assistance is high at 55 percent, whereas women who are not receiving social assistance, the poverty rate for non-elderly women are 17 percent. For unattached wo...

Global Economic Freedom is an issue that we as conscious business people should be aware of. It is not enough just to know the rules and laws that govern the economic system in ones own country.

Global Economic Freedom is an issue that we as conscious business people should be aware of. It is not enough just to know the rules and laws that govern the economic system in ones own country. Global Economic Freedom is an issue that we as conscious business people should be aware of. It is not enough just to know the rules and laws that govern the economic system in one's own country. With the continued expansion in global business it is almost certain that a business dealing with foreign countries will need to have a general idea about the foreign countries economic system and the general rules and laws that govern that economic system. Depending on the country's economic system, whether it is free or not, can have a substantial impact on whether a business can be profitable in a foreign country and therefore will have an influence over whether a company operates or has business relations in a specific country.With this in mind I will discuss what Economic Freedom is and will also examine the national economies of the United Kingdom, which is ranked economically free at #7, and Iran, which is ranked economically repressed at #151.Iran - Dans le dà ©sert, montagnesI will examine these countries by comparing and contrasting the two to determine why the United Kingdom is economically free and why Iran is not economically free.Economic Freedom is defined by the Wall Street Journal as "the difference between financial poverty and financial prosperity." An easy way to understand this concept, as illustrated by the Wall Street Journal, is to look at the Gross Domestic Product per-capita incomes of the countries in question and compare the two. According to the article "Who's Free, Who's Not" in the November 1, 2000 issue of the Wall Street Journal, a repressed economic country's GDP per-capita income is around $2,800 per year compared to the GDP per-capita income of an economically free country, which is around $21,200 per year. If we look at the countries under examination we see that...

Practice of Teaching in Dyslexic Students Essay

Practice of Teaching in Dyslexic Students - Essay Example It is essential to comprehend that several learning problems come up if the teacher fails to recognise dyslexia at the right time and it makes the teaching inappropriate. Understanding dyslexia as a learning difficulty involves the perception that something is 'wrong' with the learner and here the teacher's focus shifts from celebrating the strengths to identifying weaknesses. Such a perception of the students with dyslexia emphasises the remediation by specialists. However, it is essential to implement resolution by knowledgeable class and subject teachers and supported by specialist help and intervention appropriate to the needs of the students. As dyslexia is a vital problem facing many students in the contemporary educational system, it is essential to have a clear-cut knowledge about this issue as well as the ways to deal with it. It is essential for the educators to make instructional adjustments in order to make the dyslexic students successful in an academic environment. ... In a reflective analysis of the social, emotional and behavioural aspects of dyslexia, it becomes evident that the role of a teacher who caters to the various needs of dyslexic students is essential for the effective teaching practice in the area. Evidences from significant researches on the topic suggest that if dyslexia is not very early identified, it can affect the person in a vicious manner and it can lead from learning to behaviour problems and from behaviour problems to increased learning disability. The specific difficulties associated with the dyslexic students stress the importance of effective measures by teachers in classroom environment. Thus, it is essential to maintain that dyslexia affects the skills of information processing in particular working memory if the student, along with phonological awareness, labelling, rapid naming and the speed of processing. It also results in the failure to develop language and literacy skills to the expected level which in turn limits the access to curriculum in school, continuing education, and employment. Therefore, the teacher has a fundamental role in dealing with the issues faced by the dyslexic students. In the UK, it is currently believed that the dyslexic students process information differently than other children. Thus, if the teacher takes this difference in processing information into account, these students can learn effectively, although perhaps more slowly in relation to literacy. Therefore, this paper makes a profound analysis of how the teacher can make the classroom dyslexia friendly and the lessons more accessible to the student. It also attempts to investigate how structured, multisensory teaching,

Business Failure Essay Example | Topics and Well Written Essays - 10000 words

Business Failure - Essay Example The following year saw liquidity dry up, businesses lose their orders or defaulting on their payments, and layoffs become widespread. Then, businesses started closing; the larger conglomerates relied upon government bailout money, at the risk of nationalization, but â€Å"too large to fail† was exactly that – critical industries and the economic framework relied upon the survival of these key enterprises (Peters, Shane & Torgerson, 2009). While there were some companies that were saved at all costs – especially at the cost of public money being used to purchase toxic assets – other companies were left to die out because they were not crucial to the coming recovery. Several of these hardest hit are in the retail sales business. And in the United Kingdom, one of these companies that had to close its books for the last time was Woolworths, the high-street retail firm in existence since 1909, and owned by the Woolworths Group plc. This case study shall deal with the phenomenon of business failure, and its occurrence in the UK retail sector. Highlighted will be the case of Woolworths plc, which presents several controversies concerning the circumstances surrounding its closure. The case of Woolworths is one that defies an easy and clear-cut solution; as many serious observers believe that the company should not have been closed down because its two or three core businesses could have been demerged and allowed to operate; apparently, the administrators and regulators felt otherwise, and finalized the group’s demise. A small remnant of Woolies (as it is affectionately called) continues to operate as an online retailer, having been acquired by the Shop Direct Group (Anon, Cabinet Maker, 2009). This study shall examine the case of Woolworths from the point of view of theory, and from the indicators and accounts that comprised the facts of its operations.